2,4-Difluoro-alpha-(1H-1,2,4-triazolyl)acetophenone CAS#86404-63-9

1.Important Pharmaceutical Intermediate: It serves as a key chemical building block for scientists in the synthesis of pharmaceutical compounds, especially antifungal drugs such as voriconazole.

2.High Structural Value in Drug Synthesis: Its unique chemical structure makes it an essential intermediate for developing and producing triazole-based antifungal agents.

3.Reliable Reference Standard: It is used as an official reference standard for evaluating the purity and quality of existing pharmaceutical products.

4.Stable Solid Form and Convenient Handling: Available as a white to off-white solid powder, it offers stable physical properties suitable for laboratory and pharmaceutical research applications.

Product Description

2,4-Difluoro-α-(1H-1,2,4-triazolyl)acetophenone (CAS No.: 86404-63-9) is an important chemical intermediate used by researchers for pharmaceutical synthesis. It serves as a key structural component in the preparation of antifungal drugs, including voriconazole. The compound is typically present as a white to off-white solid and is also used as an official reference standard for evaluating the purity of existing pharmaceutical products.

2,4-Difluoro-alpha-(1H-1,2,4-triazolyl)acetophenone CAS#86404-63-9

Properties

Melting point 103-107 °C(lit.)
Boiling point 388.0±52.0 °C(Predicted)
density 1.39±0.1 g/cm3(Predicted)
storage temp. 2-8°C
solubility Chloroform (Slightly), Methanol (Slightly)
form Solid
pka2.05±0.10(Predicted)
color White to pale brown
CAS DataBase Reference86404-63-9(CAS DataBase Reference)
Safety Statements 24/25
WGK Germany 3
HS Code 29339900

Product Application

2',4'-Difluoro-2-[1-(1H-1,2,4-triazolyl)]acetophenone is an important intermediate used in the synthesis of antifungal agents such as voriconazole, with broad applications in the pharmaceutical industry. It can also serve as a reagent in biochemical and life science research, where it is involved in the construction of complex organic molecular structures.

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