Product Description
Benzhydrylpiperazine, also known as 1-Benzhydrylpiperazine or N-(Diphenylmethyl)piperazine, is a piperazine derivative that appears as a white solid at room temperature. It is soluble in organic solvents such as ethanol, benzene, and toluene, while its solubility in water is only 0.45 g/L at 20°C.
Benzhydrylpiperazine is a toxic chemical and may be harmful if ingested. Appropriate safety measures should be taken to avoid contact with skin and eyes. As it is sensitive to air, the formation of dust and aerosols should be minimized during handling. Its molecular formula is C₁₇H₂₀N₂.
Properties
| Melting point | 90-93 °C |
| Boiling point | 185°C/2mmHg(lit.) |
| density | 1.0546 (rough estimate) |
| vapor pressure | 0.001Pa at 20℃ |
| refractive index | 1.5794 (estimate) |
| Fp | 115 °C |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | Methanol (Slightly) |
| form | Crystalline Powder |
| pka | 9.05±0.10(Predicted) |
| color | White to light yellow |
| Water Solubility | 0.45 g/L (20 ºC) |
| Sensitive | Air Sensitive |
| BRN | 222773 |
| LogP | 0.6 at 20℃ |
| CAS DataBase Reference | 841-77-0(CAS DataBase Reference) |
| NIST Chemistry Reference | Benzhydryl piperazine(841-77-0) |
| Hazard Codes | Xn,Xi |
| Risk Statements | 22 |
| Safety Statements | 22-24/25 |
| WGK Germany | 3 |
| RTECS | TL6465000 |
| F | 34 |
| HazardClass | IRRITANT |
| HS Code | 29339900 |
Product Application
1-Benzhydrylpiperazine is used as an intermediate in organic synthesis and pharmaceutical synthesis. It can be applied in the preparation of antihistamine drugs, including the H1-receptor antagonist Oxatomide.
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