Product Description
Selecting a suitable counter ion is crucial for enhancing the solubility and bioavailability of pharmaceutical compounds. Meglumine (N-methyl-D-glucosamine) is a widely used counter ion that effectively improves drug solubility. It is an amino sugar derived from sorbitol and has a pKa value of 9.6, making it valuable in pharmaceutical formulations.
Properties
| Melting point | 129-131.5 °C (lit.) |
| alpha | -16.5 º (c=10, H2O, on dry sub) |
| Boiling point | 331.88°C (rough estimate) |
| density | 1.2669 (rough estimate) |
| refractive index | -16.5 ° (C=2, H2O) |
| RTECS | LZ4295770 |
| storage temp. | 2-8°C |
| solubility | H2O: 0.1 g/mL, clear, colorless |
| form | Crystalline Powder |
| pka | pKa 9.39(H2O,t =30.0,I=0.05N2)(Approximate) |
| color | White to almost white |
| PH | 11 (10g/l, H2O, 20℃) |
| optical activity | [α]20/D 16.5±0.5°, c = 2% in H2O |
| Water Solubility | 100 g/100 mL (25 ºC) |
| Sensitive | Air Sensitive & Hygroscopic |
| Merck | 146078 |
| BRN | 385906 |
| InChIKey | MBBZMMPHUWSWHV-VZFHVOOUSA-N |
| LogP | -3.370 (est) |
| NIST Chemistry Reference | N-methylglucamine(6284-40-8) |
| EPA Substance Registry System | Meglumine (6284-40-8) |
Safety Information
| Risk Statements | 36/37/38 |
| Safety Statements | 24/25 |
| WGK Germany | 3 |
| F | 37917 |
| Autoignition Temperature | ~662 °F |
| TSCA | Yes |
| HS Code | 29221980 |
| Toxicity | LD50 orally in Rabbit: > 5000 mg/kg |
Product Application
As a cosolvent and surfactant in contrast agents. Diagnostic drugs, used as a cosolvent and surfactant in contrast agents.
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Company Profile
Shandong Rongsheng Chemical Co., Ltd. operates out of Shandong’s key chemical industrial hub. As a full‑fledged chemical enterprise covering production, R&D, domestic sales and international exports, we focus on supplying basic chemical raw materials and fine chemical additives. Our products serve numerous industries, including rubber and plastic processing, coatings and inks, water treatment, and general‑purpose industrial manufacturing.
We own standardized in‑house production facilities and carry out independent quality checks across the whole manufacturing workflow, allowing us to supply goods directly from our factory. Without extra price increases brought by middle‑party distributors, we can satisfy varied business needs. Our service portfolio comprises large‑volume bulk orders, custom formula adjustment, special packaging solutions and small‑batch sample supplies. We can rearrange production plans flexibly to match individual customer requirements and ensure stable deliveries.
Our specialist international trade team has accumulated rich hands‑on experience across global chemical markets. Thoroughly familiar with import compliance standards and cross‑border logistics rules of different countries, we offer overseas buyers comprehensive export assistance. Our service chain includes inquiry responses, sample distribution, custom solution design, customs filing, cargo shipment and continuous after‑sales assistance.
We follow our core business values: quality‑centered operation and integrity‑guided win‑win cooperation. Drawing on stable product performance, varied service options as well as efficient and regulatory‑compliant shipping capability, we provide cost‑effective and high‑reliability chemical supply‑chain solutions for global purchasers. We aim to develop long‑term trust‑built relationships and become a trusted cooperative partner for fine‑chemical trade on a global scale.
